If its from a quality site,then yes,its safe..There are better platforms to get links from,if i were you i'd focus on contextuals more and mix it up with low obl blog comments.
I personally love them. Like young_gooner said above, if you are direct to the money site, then only high quality. That applies to any direct link to the money site. TB's get you websites that you would otherwise never have a link on as many do not allow comments but they allow trackbacks
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